

The AEGIS Microbe
Shield Program and its cornerstone chemistry AEM 5700 is registered
in Canada with the Pest Management Regulatory Agency (PMRA) under
the Pest Control Products Act, registration number 15133. Similar
registrations with the United States Environmental Protection
Agency (USEPA) and Federal Insecticide, Fungicide and Rodenticide
Act (FIFRA) are in force in the USA for similar usages. AEM
5700 is approved for use in Canada as a material preservative
to be applied on-site to all indoor non-food contact porous and
non-porous surfaces. Due
to its inherent bonding mechanism, which eliminates concerns
with dislodgeable residues, it is not considered a topical disinfectant
or sanitiser and, as such, does not require registration with
the Therapeutic Products Program. AEM 5700, at time of
writing, is the only antimicrobial specifically permitted to
be used in sheet metal non-porous duct systems in Canada due
this inherent safety.
AEGIS is a permanent antimicrobial that, when applied
properly only by our trained applicators, becomes part of a new
surface, a surface that is highly resistant to microbial attack. Unlike all
other conventional antimicrobials, AEGIS does
not off gas, leach, diffuse, migrate, volatilise, or otherwise
leave the surface to which it has been applied. The result
is an extraordinary safety and efficacy profile unmatched by other
products.
Antimicrobials can be divided into two major
categories; bound and unbound. These terms refer to whether or
not the antimicrobial has the capacity to molecularly bond to
the surface on which it is applied. An UNBOUND must
diffuse or leach from the treated surface and be consumed by
the microorganism to be effective. Most conventional antimicrobials
are intended to act quickly and dissipate quickly to minimize
the danger to humans, animals and treated objects. Others use
the time release capsule approach and obtain a longer working
life by burying the antimicrobial in a paint, glue, binder or
other coating and counting on slow migration to the surface.
Conventional antimicrobials, even those applied in a carrier,
must diffuse and create a Azone of inhibition@ in order to function
properly. Once inside the organism, the chemical agent will act
like a poison, interrupting some key metabolic, or life sustaining
process of the cell and causing it to die. Once the antimicrobial
is depleted or washed away during regular maintenance, protection
vanishes. After application, an unbound antimicrobial continues
to diffuse or leach from the treated surface. As this diffusion
continues, the concentration of the active ingredient eventually
becomes diluted below effective levels. Under these conditions,
microorganisms have the ability to adapt or build up a tolerance
to these particular antimicrobials. Highly resistant strains
can develop which are immune to what was once an effective dose.
A BOUND ANTIMICROBIAL agent, like the AEGIS Microbe
Shield, remains chemically attached to the surface on which it
is applied. It functions by interrupting the organism's delicate
cell membrane. This prevents microorganisms from carrying on
vital life processes. This antimicrobial acts on contact with
organisms and can do so again and again. One can think of the
bound antimicrobial like a sword which is capable of repeated
use. In comparison, a conventional antimicrobial treatment is
more like a gun with limited ammunition. Since a Abound@ antimicrobial
is fixed to the surface it continually operates at full strength.
This means the genetic adaptation process, which is an inherent
problem with conventional antimicrobials, cannot and does not
occur with a bound antimicrobial.
The chemistry of the product is unique. A
conventional quaternary ammonium salt is chemically spliced to
a silane molecule, resulting in a highly active molecule
(3-trimethoxysilylpropyldimethyloctadecyl
ammonium chloride) that has both tenacious bonding capabilities
as well as excellent antimicrobial properties. Once applied
to a target surface it initially bonds to the surface on all
available receptor sites (principally H+). Afterward, stable
bonds between remaining OH- sites on the molecule and the positive
charge on the nitrogen atoms (N+) form, resulting in the creation
of a large co-polymer involving the target and AEM 5700. Since
there is no unused residue once the water evaporates, there is
no dislodgeable residue and no odour, leaching, off-gassing,
migration or diffusion of the molecule can occur.
All other conventional antimicrobials used legally in Canada,
including quats, bleach, peroxides, phenols, triclosan, formaldehydes,
paint formulations, etc., work on the basis of diffusion away from
the treated surface. This promotes adaptation, loss of activity,
leaching, diffusion, and creation of zones of inhibition. AEM 5700
(formally Dow Corning 5700) is essentially permanent, and these
problems associated with conventional chemicals are not of concern. |